Article

DNA methylation-based age acceleration observed in IDH wild-type glioblastoma is associated with better outcome - including in elderly patients

2022-02-04

Abstract excerpt

Elderly patients represent a growing proportion of individuals with glioblastoma, who however, are often excluded from clinical trials owing to poor expected prognosis. Little is known about molecular features that would justify different treatment modalities, not related to frailty and co-morbidities. We investigated the DNA methylome (450k) for age related associations using 4 different glioblastoma datasets (me...

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Literature Corpus work: 27f766bf-5cd6-53ce-89f9-8f72b2eb1f1e
DOI: 10.1101/2022.02.03.22270104

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