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Article

Associations of DNA methylation algorithms of aging and cancer risk: Results from a prospective cohort study

27 May 2022

Abstract excerpt

BACKGROUND: Previous studies have shown that three DNA methylation (DNAm) based algorithms of aging, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality risk score (MRscore), to be strong predictors of mortality and aging related outcomes. We aimed to investigate if and to what extent these algorithms predict cancer. METHODS: In four subsets (n = 727, 1003, 910, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35636319
DOI: 10.1016/j.ebiom.2022.104083

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