Article
Age-specific signatures of glioblastoma at the genomic, genetic, and epigenetic levels.
PloS one - 1 Jan 2013
Bozdag Serdar, Li Aiguo, Riddick Gregory, Kotliarov Yuri, Baysan Mehmet, Iwamoto Fabio M, Cam Margaret C, Kotliarova Svetlana, Fine Howard A
Abstract excerpt
Age is a powerful predictor of survival in glioblastoma multiforme (GBM) yet the biological basis for the difference in clinical outcome is mostly unknown. Discovering genes and pathways that would explain age-specific survival difference could generate opportunities for novel therapeutics for GBM. Here we have integrated gene expression, exon expression, microRNA expression, copy number alteration, SNP, whole...
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