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The IL-10 <sup>GFP</sup> (VeRT-X) mouse strain is not suitable for the detection of IL-10 production by granulocytes during lung inflammation

2021-02-17

Abstract excerpt

The clear and unequivocal identification of immune effector functions is essential to understand immune responses. The cytokine IL-10 is a critical immune regulator and was shown, for example, to limit pathology during various lung diseases. However, the clear identification of IL-10-producing cells is challenging and, therefore, reporter mouse lines were developed to facilitate their detection. Several such repor...

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Literature Corpus work
27dc6647-6f46-518b-9968-948540858783
DOI
10.1101/2021.02.17.431604
Open publication

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The IL-10 <sup>GFP</sup> (VeRT-X) mouse strain is not suitable for the detection of IL-10 production by granulocytes during lung inflammationDOI 10.1101/2021.02.17.431604
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