Transgenic modelling of cytokine polarization in the lung.

doi:10.1111/j.1365-2567.2010.03376.x

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Article

Transgenic modelling of cytokine polarization in the lung.

Immunology - 1 Jan 2011

Dela Cruz Charles S, Kang Min-Jong, Cho Won-Kyung, Lee Chun Geun

Abstract excerpt

The lung is one of the commonest sites of exposure to environmental allergen or pathogen, so the expression of a variety of cytokines in the lung is dynamically regulated by inflammatory or structural cells in the lung. In the last decades, characterization of the local lung cytokine milieu in allergic or injury models has identified a collective role of certain cytokines, such as type 1 or type 2 cytokines,...

Topics

Animals
Cytokines
Inflammation
Lung
Mice
Mice, Transgenic
Models, Immunological
Phenotype

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Identifiers

PMID: 21091906
DOI: 10.1111/j.1365-2567.2010.03376.x
PMCID: PMC3015070

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