Article
Detection of experimentally induced pulmonary granuloma inflammation in monocyte chemoattractant protein-1 reporter mice.
Molecular imaging and biology - 1 Apr 2010
Rajasekaran Subbiah, Kao Vivia Yu-Ying, Chen Mei-Ru, Yang Alex Liang-Tung, Hsu Ching-Han, Chen Chin-Tu, Lin Kurt Ming-Chao
Abstract excerpt
PURPOSE: Among different chemokines, monocyte chemoattractant protein-1 (MCP-1) plays an important role in inflammatory disorders of lung. In response to stimuli, MCP-1 increases its transcription as an immediate early gene. In this paper, we describe the MCP-1-enhanced green fluorescent protein(EGFP) transgenic mouse in which EGFP expression is driven by human MCP-1 promoter and mimics the MCP-1 expression in...
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