Article
STOP floxing around: Specificity and leakiness of inducible Cre/loxP systems.
European journal of immunology - 1 Mar 2020
Stifter Sebastian A, Greter Melanie
Abstract excerpt
Cre and CreER mouse strains are powerful tools that have proven invaluable for investigating the function of genes and for the fate-mapping of cell populations. The fidelity of these systems however are becoming more and more contested. In this issue of the European Journal of Immunology, Van Hove et al. and Chappell-Maor et al. carefully dissect the cellular specificities of two commonly used CreER mouse strains...
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