Article
IL-10-Producing Potential Treg Precursor in Placenta.
The Kurume medical journal - 23 Jan 2020
Yano Arisa
Abstract excerpt
The maternal immune system needs to be tolerant of allogeneic fetal tissue for reproductive success. The regulatory immune cell network plays an essential role in maintaining maternal tolerance to the fetus. We herein demonstrate in a green fluorescent protein (GFP)/IL-10 reporter mouse system that unique IL-10-expressing cells exist presumably in chorionic villi within the placenta. Flow cytometric analysis...
Topics
- Adoptive Transfer
- Animals
- Antigens, CD19
- Antigens, Ly
- CD3 Complex
- Cell Lineage
- Cells, Cultured
- Female
- Genes, Reporter
- Green Fluorescent Proteins
- Immunocompromised Host
- Interleukin-10
