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Article

Novel, Non-Gene-Destructive Knock-In Reporter Mice Refute the Concept of Monoallelic Gata3 Expression.

Journal of immunology (Baltimore, Md. : 1950) - 1 May 2020

Rao Tata Nageswara, Kumar Suresh, Pulikkottil Alex Jose, Oliveri Franziska, Hendriks Rudi W, Beckel Franziska, Fehling Hans Joerg

Abstract excerpt

Accurately tuned expression levels of the transcription factor GATA-3 are crucial at several stages of T cell and innate lymphoid cell development and differentiation. Moreover, several lines of evidence suggest that Gata3 expression might provide a reliable molecular marker for the identification of elusive progenitor cell subsets at the earliest stages of T lineage commitment. To be able to faithfully monitor...

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Identifiers

PMID: 32213568
DOI: 10.4049/jimmunol.2000025
PMCID: PMC7167461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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