Article

KappaBle fluorescent reporter mice enable dynamic and low-background single-cell detection of NF-κB activity <i>in vivo</i>

2021-09-03

Abstract excerpt

Nuclear factor-κB (NF-κB) is a transcription factor with a key role in a great variety of cellular processes from embryonic development to immunity, the outcome of which depends on the fine-tuning of NF-κB activity. The development of sensitive and faithful reporter systems to accurately monitor the activation status of this transcription factor is therefore desirable. To address this need, over the years a number...

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Literature Corpus work: f130878a-6313-509c-86f1-22648e92f06a
DOI: 10.1101/2021.09.02.458704

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