Article

Curcumin-mediated NRF2 induction limits inflammatory damage in preclinical models of cystic fibrosis

2024-03-17

Abstract excerpt

Overactive inflammation is directly correlated with airway damage and early death in individuals with cystic fibrosis (CF), a genetic disorder caused by mutation in the CFTR gene. Reducing the impact of inflammatory damage is therefore a major concern in CF. Several studies indicate that a decrease in the nuclear factor erythroid 2-related factor-2 (NRF2) signaling in people with CF may hamper their ability to al...

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Literature Corpus work: 27cc81dc-6e0d-5793-8e26-23d0d87ff310
DOI: 10.1101/2024.03.17.585384

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