Article

Regulation of ATM and ATR by Smarcal1 and BRG1

2018-02-08

Abstract excerpt

<h4>ABSTRACT</h4> The G2/M checkpoint is activated on DNA damage by the ATM and ATR kinases that are regulated by post-translational modifications. In this paper, the transcriptional co-regulation of ATM and ATR by SMARCAL1 and BRG1, both members of the ATP-dependent chromatin remodeling protein family, is described. SMARCAL1 and BRG1 co-localize on the promoters of ATM and ATR ; downregulation of SMARCAL1/BR...

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Literature Corpus work: 27af4f41-825d-53d6-b9d2-63e4f1b468fe
DOI: 10.1101/261610

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