Article
SMARCAL1, the annealing helicase and the transcriptional co-regulator.
IUBMB life - 1 Oct 2020
Bansal Ritu, Hussain Saddam, Chanana Upasana Bedi, Bisht Deepa, Goel Isha, Muthuswami Rohini
Abstract excerpt
The ATP-dependent chromatin remodeling proteins play an important role in DNA repair. The energy released by ATP hydrolysis is used for myriad functions ranging from nucleosome repositioning and nucleosome eviction to histone variant exchange. In addition, the distant member of the family, SMARCAL1, uses the energy to reanneal stalled replication forks in response to DNA damage. Biophysical studies have shown...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
