Article
The ATM-dependent DNA damage signaling pathway.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2005
Kitagawa R, Kastan M B
Abstract excerpt
Many of the insights that we have gained into the mechanisms involved in cellular DNA damage response pathways have come from studies of human cancer susceptibility syndromes that are altered in DNA damage responses. ATM, the gene mutated in the disorder, ataxia-telangiectasia, is a protein kinas...
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