Article

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

2019-03-24

Abstract excerpt

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine carcinoma of the skin mediated by the integration of Merkel cell polyomavirus (MCPyV) and expression of viral T antigens or by ultraviolet induced damage to the tumor genome from excessive sunlight exposure. An increasing number of deep sequencing studies of MCC have identified significant differences between the number and types of point mutations,...

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Literature Corpus work: 2796b6aa-c80c-59e0-bdfd-dda525e8b19d
DOI: 10.1101/587626

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