Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Merkel Cell Carcinoma from Molecular Pathology to Novel Therapies

11 Jun 2021

Abstract excerpt

Merkel cell carcinoma (MCC) is an uncommon and highly aggressive skin cancer. It develops mostly within chronically sun-exposed areas of the skin. MCPyV is detected in 60–80% of MCC cases as integrated within the genome and is considered a major risk factor for MCC. Viral negative MCCs have a high mutation burden with a UV damage signature. Aberrations occur in RB1, TP53, and NOTCH genes as well as in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antenna Design and Analysis
Share to Full-Duplex Wireless Communications
Share to Polyomavirus and related diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34208339
DOI: 10.3390/ijms22126305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Merkel Cell Carcinoma from Molecular Pathology to Novel TherapiesPMID 34208339Read ↗

Update on Merkel Cell Carcinoma.Semantic proximity Read ↗

Merkel cell carcinoma: an updated overview of clinico-pathological aspects, molecular genetics and therapy.Semantic proximity Read ↗

Danger is only skin deep: aggressive epidermal carcinomas. An overview of the diagnosis, demographics, molecular-genetics, staging, prognostic biomarkers, and therapeutic advances in Merkel cell carcinoma.Semantic proximity Read ↗

Merkel cell carcinoma.Semantic proximity Read ↗

UV-Associated Mutations Underlie the Etiology of MCV-Negative Merkel Cell Carcinomas.Semantic proximity Read ↗

Molecular Pathogenesis of Merkel Cell Carcinoma.Semantic proximity Read ↗

Mutational Analysis of Merkel Cell CarcinomaSemantic proximity Read ↗

Epidemiology of Merkel Cell Polyomavirus Infection and Merkel Cell CarcinomaSemantic proximity Read ↗

From Merkel Cell Polyomavirus Infection to Merkel Cell Carcinoma OncogenesisSemantic proximity Read ↗

Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy.Semantic proximity Read ↗

Merkel cell carcinoma: more deaths but still no pathway to blame.Semantic proximity Read ↗

Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.