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Article

The catalytic significance of the proposed active site residues in Plasmodium falciparum histoaspartic protease.

The FEBS journal - 1 Apr 2008

Parr Charity L, Tanaka Takuji, Xiao Huogen, Yada Rickey Y

Abstract excerpt

Alanine mutations of the proposed catalytically essential residues in histoaspartic protease (HAP) (H34A, S37A and D214A) were generated to investigate whether: (a) HAP is a serine protease with a catalytic triad of His34, Ser37 and Asp214 [Andreeva N, Bogdanovich P, Kashparov I, Popov M & Stengach M (2004) Proteins55, 705-710]; or (b) HAP is a novel protease with Asp214 acting as both the acid and the base...

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Share to Aspartic Acid Endopeptidases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18312598
DOI: 10.1111/j.1742-4658.2008.06325.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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