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Single-Cell RNA Sequencing Reveals Characteristics of Myeloid Cells and Fibroblasts in RAS-Mutated Colorectal Cancer

2025-07-03

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<title>Abstract</title> <p>Background <italic>RAS</italic>-mutated (RAS-mut) colorectal cancer (CRC) has poor prognosis and is resistant to immune therapies. Therefore, understanding the mechanism of immune evasion in RAS-mut CRC is crucial for developing new therapeutic targets. Methods A total of 36 clinical surgical samples (tumors and paired adjacent tissues) from 18 patients with primary CRC were collected...

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Literature Corpus work: 27712a9e-fcf8-5aa8-b364-6057cd666a48
DOI: 10.21203/rs.3.rs-6741598/v1

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