Article
Infant antibody repertoires during the first two years of influenza vaccination
2022-09-15
Abstract excerpt
The first encounter with influenza virus biases later immune responses. This “immune imprinting”, formerly from infection within a few years of birth, is in the U.S. now largely from immunization with a quadrivalent, split vaccine (IIV4). In a pilot study of IIV4 imprinting, we characterized, by single-B-cell cultures, NextGen sequencing, and plasma antibody proteomics, the primary antibody responses to influenza...
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Identifiers and source
- Literature Corpus work
- 271f1b4b-91ec-51ae-a60b-319d1d05052f
- DOI
- 10.1101/2022.09.13.507806