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Article

Differential immune imprinting by influenza virus vaccination and infection in nonhuman primates

31 May 2021

Abstract excerpt

Immune memory of a first infection with influenza virus establishes a lasting imprint. Recall of that memory dominates the response to later infections or vaccinations by antigenically drifted strains. Early childhood immunization before infection may leave an imprint with different characteristics. We report here a comparison of imprinting by vaccination and infection in a small cohort of nonhuman primates...

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PMID: 34074774
DOI: 10.1073/pnas.2026752118

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