Article

ABCA7-dependent Neuropeptide-Y signalling is a resilience mechanism required for synaptic integrity in Alzheimer’s disease

2024-01-02

Abstract excerpt

Alzheimer’s disease (AD) remains a complex challenge characterized by cognitive decline and memory loss. Genetic variations have emerged as crucial players in the etiology of AD, enabling hope for a better understanding of the disease mechanisms; yet the specific mechanism of action for those genetic variants remain uncertain. Animal models with reminiscent disease pathology could uncover previously uncharacterize...

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Literature Corpus work: 26dfd81d-9a33-5cf5-9b24-b5d5e8933ae7
DOI: 10.1101/2024.01.02.573893

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