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Article

The ABC's of Alzheimer risk gene ABCA7.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 May 2024

Duchateau Lena, Wawrzyniak Nicole, Sleegers Kristel

Abstract excerpt

Alzheimer's disease (AD) is a growing problem worldwide. Since ABCA7's identification as a risk gene, it has been extensively researched for its role in the disease. We review its recently characterized structure and what the mechanistic insights teach us about its function. We furthermore provide an overview of identified ABCA7 mutations, their presence in different ancestries and protein domains and how they...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38556850
DOI: 10.1002/alz.13805
PMCID: PMC11095487

Genes

ABCA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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