Article

Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage

2022-02-02

Abstract excerpt

Each mammalian autosomal gene is represented by two alleles in diploid cells. Yet, no insights have been made in regard to allele-specific regulatory mechanisms of autosomes. Here we used allele-specific single cell transcriptomic analysis to elucidate the establishment of monoallelic gene expression in the cardiac lineage. We found that monoallelically expressed autosomal genes in mESCs and mouse blastocyst cells...

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Literature Corpus work: 26784940-1f40-51f1-be02-9546a3aaaa5e
DOI: 10.1101/2022.02.01.478691

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