Article
The influence of DNA methylation on monoallelic expression.
Essays in biochemistry - 20 Dec 2019
da Rocha Simão Teixeira, Gendrel Anne-Valerie
Abstract excerpt
Monoallelic gene expression occurs in diploid cells when only one of the two alleles of a gene is active. There are three main classes of genes that display monoallelic expression in mammalian genomes: (1) imprinted genes that are monoallelically expressed in a parent-of-origin dependent manner; (2) X-linked genes that undergo random X-chromosome inactivation in female cells; (3) random monoallelically expressed...
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