Article

Cell-type specialization in the brain is encoded by specific long-range chromatin topologies

2020-04-02

Abstract excerpt

Neurons and oligodendrocytes are terminally differentiated cells that sustain cascades of gene activation and repression to execute highly specialized functions, while retaining homeostatic control. To study long-range chromatin folding without disturbing the native tissue environment, we developed Genome Architecture Mapping in combination with immunoselection (immunoGAM), and applied it to three cell types from...

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Literature Corpus work: 265c8d0c-6798-5959-9bb5-db6c54959844
DOI: 10.1101/2020.04.02.020990

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