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Methicillin-Resistant <i>Staphylococcus aureus</i> has Phenotypic Variation in <i>mecA</i> Expression that Alters Antibiotic Sensitivity

2025-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Methicillin resistant Staphylococcus aureus (MRSA) sepsis has a high rate of morbidity and mortality. Multiple clinical studies have demonstrated improved outcomes when MRSA sepsis is treated with dual antibiotic therapy that includes a β-lactam antibiotic such as cefazolin. This is a paradox as MRSA should be inherently resistant to this class of antibiotics. We report a serendipitous observat...

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Literature Corpus work
264fca06-232d-5b2d-b7af-b7aa6b0430ae
DOI
10.1101/2025.05.28.656574
Open publication

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Methicillin-Resistant <i>Staphylococcus aureus</i> has Phenotypic Variation in <i>mecA</i> Expression that Alters Antibiotic SensitivityDOI 10.1101/2025.05.28.656574
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