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<i>Staphylococcus aureus</i> COL: An Atypical Model Strain of MRSA that Exhibits Slow Growth and Antibiotic Tolerance Due to a Mutation in PRPP Synthetase

2024-12-12

Abstract excerpt

<h4>Summary</h4> Methicillin-resistant Staphylococcus aureus (MRSA) has been a pathogen of global concern since its emergence in the 1960s. As one of the first MRSA strains isolated, COL has become a common model strain of S. aureus . Here we report that COL is, in fact, an atypical strain of MRSA that exhibits slow growth and multidrug tolerance. Genomic analysis identified three mutated genes in COL ( rpoB,...

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Literature Corpus work
7a6438a1-d710-580f-9e2d-383a89accc38
DOI
10.1101/2024.12.12.627954
Open publication

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<i>Staphylococcus aureus</i> COL: An Atypical Model Strain of MRSA that Exhibits Slow Growth and Antibiotic Tolerance Due to a Mutation in PRPP SynthetaseDOI 10.1101/2024.12.12.627954
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