Article

An Update on the Role of Penicillin Binding Protein-4 (PBP4) in β-Lactam Resistance of <em>Staphylococcus aureus</em>

2026-01-20

Abstract excerpt

Staphylococcus aureus remains to be one of the leading causes of global mortality. The most common class of antibiotics used to treat S. aureus infections are Next-Generation β-lactams (NGBs), as they are highly efficacious and have low adverse effects. NGB resistance in S. aureus is classically attributed to Penicillin-Binding Protein-2a (PBP2a), but previous studies from our group have also implicated altered ex...

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Literature Corpus work: 7c5d4953-1ccb-5a5e-9a94-707b4edd2d33
DOI: 10.20944/preprints202601.1446.v1

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