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Key Genetic Elements and Regulation Systems in Methicillin-Resistant <i>Staphylococcus Aureus</i>

17 Oct 2012

Abstract excerpt

Methicillin-resistant Staphylococcus aureus (MRSA), popularly known as a type of superbug, has been a serious challenge for animal and human health. S. aureus has developed methicillin resistance mainly by expression of β-lactamase and PBP2a, which is regulated by the blaZ-blaI-blaR1 and mecA-mecI-mecRI systems. Other genetic elements, including murE and femA, also participate in expression of methicillin...

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PMID: 23075449
DOI: 10.2217/fmb.12.107

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