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Uncovering the mechanisms of clinically-relevant altered antibiotic responses of <i>Staphylococcus aureus</i> under wound infection-mimetic conditions

2025-12-23

Abstract excerpt

<h4>Summary</h4> Standard in vitro antimicrobial susceptibility testing (AST) using Mueller-Hinton broth (MHB) does not reflect infection-site conditions, and its results often do not correlate with therapeutic outcomes. Here, we compared the antibiotic susceptibility of methicillin-resistant Staphylococcus aureus (MRSA), a common chronic wound pathogen, in simulated wound fluid (SWF) resembling wound exudate v...

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Literature Corpus work
02c56a0c-cd24-5348-8fb2-caf9c5d8b423
DOI
10.64898/2025.12.22.696073
Open publication

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Uncovering the mechanisms of clinically-relevant altered antibiotic responses of <i>Staphylococcus aureus</i> under wound infection-mimetic conditionsDOI 10.64898/2025.12.22.696073
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