Article
Targeting the LINC00324/miR-16-5p/SEPT2 Signaling Cascade is Effective to Reverse Malignant Phenotypes in Glioblastoma.
Anti-cancer agents in medicinal chemistry - 1 Jan 2023
Chen Bo, Lin Pengzhen, Li Nan
Abstract excerpt
BACKGROUND: Long non-coding RNAs (LncRNAs) are identified as pivotal regulators and biomarkers for glioblastoma (GBM). However, the role of a novel LncRNA LINC00324 in regulating GBM progression has not been fully studied in the existing publications. OBJECTIVE: In this study, we evidenced LINC00324 to act as an oncogene to facilitate GBM development, and the underlying mechanisms have also been uncovered....
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