Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pin1-Nanog expression in human glioma is correlated with advanced tumor progression

23 May 2013

Abstract excerpt

The stemness gene Nanog has been shown to play an important role in tumor development, including glioma. Nanog is phosphorylated at multiple Ser/Thr-Pro motifs, which promotes the interaction between Nanog and the prolyl isomerase Pin1, leading to Nanog stabilization by suppressing its ubiquitination. The present study investigated the expression and relationship of Pin1 and Nanog in human gliomas. Significantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neuroblastoma Research and Treatments
Share to Signaling Pathways in Disease
Share to Toxin Mechanisms and Immunotoxins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23708493
DOI: 10.3892/or.2013.2481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pin1-Nanog expression in human glioma is correlated with advanced tumor progressionPMID 23708493Read ↗

Phosphorylation stabilizes Nanog by promoting its interaction with Pin1.Semantic proximity Read ↗

Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding QuestionsSemantic proximity Read ↗

GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2ASemantic proximity Read ↗

Prognostic significance of NANOG expression in solid tumors: a meta-analysisSemantic proximity Read ↗

Phosphorylation of Nanog is essential to regulate Bmi1 and promote tumorigenesis.Semantic proximity Read ↗

LncRNA TMPO-AS1 Promotes Proliferation and Invasion by Sponging miR-383-5p in Glioma CellsSemantic proximity Read ↗

NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cellsSemantic proximity Read ↗

Regulation of NANOG in cancer cellsSemantic proximity Read ↗

Protein sumoylation with SUMO1 promoted by Pin1 in glioma stem cells augments glioblastoma malignancySemantic proximity Read ↗

LncRNA NEAT1 promotes malignant phenotypes and TMZ resistance in glioblastoma stem cells by regulating let-7g-5p/MAP3K1 axisSemantic proximity Read ↗

CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.Semantic proximity Read ↗

Expression of NANOG in human gliomas and its relationship with undifferentiated glioma cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.