Article

Bottleneck Size-Dependent Changes in the Genetic Diversity and Specific Growth Rate of a Rotavirus A Strain

2019-07-13

Abstract excerpt

<h4>ABSTRACT</h4> RNA viruses form a dynamic distribution of mutant swarm (termed “quasispecies”) due to the accumulation of mutations in the viral genome. The genetic diversity of a viral population is affected by several factors, including a bottleneck effect. Human-to-human transmission ex-emplifies a bottleneck effect in that only part of a viral population can reach the next susceptible hosts. In the present...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 25dc33e4-864a-5225-9502-707cdb70a2a6
DOI: 10.1101/702233

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bottleneck Size-Dependent Changes in the Genetic Diversity and Specific Growth Rate of a Rotavirus A StrainDOI 10.1101/702233Read

Bottleneck Size-Dependent Changes in the Genetic Diversity and Specific Growth Rate of a Rotavirus A Strain.Semantic proximity Read

The two faces of mutation: extinction and adaptation in RNA viruses.Semantic proximity Read

High mutation rates, bottlenecks, and robustness of RNA viral quasispecies.Semantic proximity Read

Intra-Population Competition during Adaptation to Increased Temperature in an RNA Bacteriophage.Semantic proximity Read

Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A VirusSemantic proximity Read

Human Rotaviruses of Multiple Genotypes Acquire Conserved VP4 Mutations during Serial Passage.Semantic proximity Read

Transmission bottlenecks as determinants of virulence in rapidly evolving pathogens.Semantic proximity Read

Inferring Transmission Bottleneck Size from Viral Sequence Data Using a Novel Haplotype Reconstruction Method.Semantic proximity Read

Negative effect of genetic bottlenecks on the adaptability of vesicular stomatitis virus.Semantic proximity Read

Population bottlenecks in quasispecies dynamics.Semantic proximity Read

Estimating viral bottleneck sizes for FMDV transmission within and between hosts and implications for the rate of viral evolutionSemantic proximity Read

Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet.Semantic proximity Read