Article

Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus

2017-01-19

Abstract excerpt

The bottleneck governing infectious disease transmission describes the size of the pathogen population transferred from a donor to a recipient host. Accurate quantification of the bottleneck size is of particular importance for rapidly evolving pathogens such as influenza virus, as narrow bottlenecks would limit the extent of transferred viral genetic diversity and, thus, have the potential to slow the rate of vir...

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Identifiers and source

Literature Corpus work: 0694f42b-0097-5cf9-81db-715725b77dd6
DOI: 10.1101/101790

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