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Article

Deep proteomic analysis of microglia reveals fundamental biological differences between model systems

2022-07-07

Abstract excerpt

Using high resolution quantitative mass spectrometry, we have generated the most comprehensive human and mouse microglia proteomic datasets to date, consisting of over 11,000 proteins across all six microglia groups. Microglia from different sources share a core protein signature of over 5600 proteins, yet fundamental differences are observed between species and culture conditions, indicating limitations for human...

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Literature Corpus work
25b10de9-b73f-5fd3-850a-84aa6515f263
DOI
10.1101/2022.07.07.498804
Open publication

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Deep proteomic analysis of microglia reveals fundamental biological differences between model systemsDOI 10.1101/2022.07.07.498804
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