Article

Mechanistic insights in to pore formation by the MACPF superfamily

2018-01-01

Abstract excerpt

Pore-forming proteins are a ubiquitous class of molecule that function in a variety of roles ranging from cellular attack to cellular defence. Despite a range of sizes and architectures, the majority of pore-forming proteins follow the same general mechanism of action, whereby soluble monomers, secreted by the host cell, bind target membranes and oligomerise to form transmembrane pores. One class of pore-forming p...

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Identifiers and source

Literature Corpus work: 258ab997-f4af-513c-b2e5-fb76c1f907c1
DOI: 10.25560/72844

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