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Article

Sequence Diversity in the Pore-Forming Motifs of the Membrane-Damaging Protein Toxins.

The Journal of membrane biology - 1 Oct 2020

Mondal Anish Kumar, Verma Pratima, Lata Kusum, Singh Mahendra, Chatterjee Shamaita, Chattopadhyay Kausik

Abstract excerpt

Pore-forming proteins/toxins (PFPs/PFTs) are the distinct class of membrane-damaging proteins. They act by forming oligomeric pores in the plasma membranes. PFTs and PFPs from diverse organisms share a common mechanism of action, in which the designated pore-forming motifs of the membrane-bound protein molecules insert into the membrane lipid bilayer to create the water-filled pores. One common characteristic of...

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Identifiers

PMID: 32955633
DOI: 10.1007/s00232-020-00141-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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