Molecular cell biology of complement membrane attack

Abstract excerpt

The membrane attack complex (MAC) is the pore-forming toxin of the complement system, a relatively early evolutionary acquisition that confers upon complement the capacity to directly kill pathogens. The MAC is more than just a bactericidal missile, having the capacity when formed on self-cells to initiate a host of cell activation events that can have profound consequences for tissue homeostasis in the face of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Burkholderia infections and melioidosis
• Share to Complement system in diseases
• Share to Erythrocyte Function and Pathophysiology