Article
Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw.
Developmental cell - 5 Feb 2018
Barske Lindsey, Rataud Pauline, Behizad Kasra, Del Rio Lisa, Cox Samuel G, Crump J Gage
Abstract excerpt
The jaw is central to the extensive variety of feeding and predatory behaviors across vertebrates. The bones of the lower but not upper jaw form around an early-developing cartilage template. Whereas Endothelin1 patterns the lower jaw, the factors that specify upper-jaw morphology remain elusive. Here, we identify Nuclear Receptor 2f genes (Nr2fs) as enriched in and required for upper-jaw formation in zebrafish....
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