Article

Cytidine monophosphate N-acetylneuraminic acid synthetase and solute carrier family 35 member A1 are required for reovirus binding and infection

2020-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Engagement of cell-surface receptors by viruses is a critical determinant of viral tropism and disease. The reovirus attachment protein, σ1, binds sialylated glycans and proteinaceous receptors to mediate infection, but the specific requirements on different cell types are unknown. To identify host factors required for reovirus-induced cell death, we conducted a CRISPR-knockout screen targeting...

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Literature Corpus work: 25331cf8-d11f-5b94-a8df-657c2f1a6c5c
DOI: 10.1101/2020.08.03.235572

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Cytidine monophosphate N-acetylneuraminic acid synthetase and solute carrier family 35 member A1 are required for reovirus binding and infectionDOI 10.1101/2020.08.03.235572Read

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