Article

CRISPR editing of candidate host factors that impact influenza A virus infection

2024-09-11

Abstract excerpt

Influenza A virus (IAV) is a respiratory pathogen with a segmented negative-sense RNA genome that can cause epidemics and pandemics. The host factors required for the complete IAV infectious cycle have not been fully identified. Here, we examined select host factors that were identified by independent CRISPR screens as candidate contributors to IAV infectivity. We performed CRISPR-mediated knockout of cytidine mon...

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Literature Corpus work: d70b8858-74e6-5575-8073-3b9cfe747c75
DOI: 10.1101/2024.09.10.612185

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