Article

The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis

2021-07-22

Abstract excerpt

<h4>ABSTRACT</h4> Engagement of host receptors is essential for viruses to enter target cells and initiate infection. Expression patterns of receptors in turn dictate host and tissue tropism and disease pathogenesis during infection. Mammalian orthoreovirus (reovirus) displays serotype-dependent patterns of tropism in the murine central nervous system (CNS) that are dictated by viral attachment protein σ1. Howeve...

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Literature Corpus work: 893865ea-8f55-5947-a384-9872beb5df1b
DOI: 10.1101/2021.07.22.453368

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