Article

Acquired Radioresistance in Cancer Associated Fibroblasts is Concomitant with Enhanced Antioxidant Potential and DNA Repair Capacity

2020-12-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Cancer-associated fibroblasts (CAFs) are a major component of the cancer stroma, and their response to therapeutic treatments likely impacts the outcome. We tested the hypothesis that CAFs develop unique characteristics that enhance their resistance to ionizing radiation. <bold>Methods</bold>: CAFs were generated through intimate coculture of normal human fibrob...

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Literature Corpus work: 2519ae13-c4f4-5fd1-8d7b-ef63728fb443
DOI: 10.21203/rs.3.rs-115117/v1

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