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Article

Bête Noire of Chemotherapy and Targeted Therapy: CAF-Mediated Resistance

16 Mar 2022

Abstract excerpt

In tumor cells’ struggle for survival following therapy, they resist treatment. Resistance to therapy is the outcome of well-planned, highly efficient adaptive strategies initiated and utilized by these transformed tumor cells. Cancer cells undergo several reprogramming events towards adapting this opportunistic behavior, leading them to gain specific survival advantages. The strategy involves changes within the...

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PMID: 35326670
DOI: 10.3390/cancers14061519

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