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Article

An Emerging Role for Calcium Signaling in Cancer-Associated Fibroblasts

21 Oct 2021

Abstract excerpt

Tumors exist in a complex milieu where interaction with their associated microenvironment significantly contributes to disease progression. Cancer-associated fibroblasts (CAFs) are the primary component of the tumor microenvironment and participate in complex bidirectional communication with tumor cells. CAFs support the development of various hallmarks of cancer through diverse processes, including direct...

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PMID: 34768796
DOI: 10.3390/ijms222111366

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