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Phosphoglucomutase A mediated regulation of carbon flux is essential for antibiotic and disease persistence in <i>Mycobacterium tuberculosis</i>

2024-06-27

Abstract excerpt

The long-term survival of Mtb mandates judicious utilization of the available resources inside the host. Uninterrupted access to host-derived nutrients holds the key to the success of Mtb. Phosphoglucomutase enzyme besides synthesizing glycogen, which serves as a nutrient reservoir, also helps modulate the carbon flux in different pathogens. Studies on the role of glycogen metabolism in disease progression, reacti...

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Literature Corpus work
213d0f36-0ad9-532c-b203-cc0afceeda72
DOI
10.1101/2024.06.27.600960
Open publication

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