Article

Engineering Quantum Dot Surfaces to Preserve Protein-DNA Interactions for Single-Molecule Visualization

2026-04-13

Abstract excerpt

<title>Abstract</title> <p>Quantum dots (QDs) are fluorescent nanoparticles widely used for single-molecule imaging because of their exceptional brightness and photostability. However, the impact of QD surface chemistry on biomolecular interactions has not been systematically investigated. Here, we report that commercial QDs unexpectedly destabilize protein-DNA complexes by inducing protein dissociation from DNA....

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Literature Corpus work: 24b9da93-2b69-5705-a7a4-191925a151ff
DOI: 10.21203/rs.3.rs-9286781/v1

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