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Article

Precisely defined protein-polymer conjugates: construction of synthetic DNA binding domains on proteins by using multivalent dendrons.

ACS nano - 1 Sept 2007

Kostiainen Mauri A, Szilvay Géza R, Lehtinen Julia, Smith David K, Linder Markus B, Urtti Arto, Ikkala Olli

Abstract excerpt

Nature has evolved proteins and enzymes to carry out a wide range of sophisticated tasks. Proteins modified with functional polymers possess many desirable physical and chemical properties and have applications in nanobiotechnology. Here we describe multivalent Newkome-type polyamine dendrons that function as synthetic DNA binding domains, which can be conjugated with proteins. These polyamine dendrons employ...

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PMID: 19206526
DOI: 10.1021/nn700053y

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