Article

Clustering-based COPD Subtypes Have Distinct Longitudinal Outcomes and Multi-omics Biomarkers

2022-01-11

Abstract excerpt

<h4>Introduction</h4> Chronic obstructive pulmonary disease (COPD) can progress across several domains, complicating the identification of the determinants of disease progression. In our previous work, we applied k-means clustering to spirometric and chest radiologic measures to identify four COPD-related subtypes: “Relatively resistant smokers (RRS)”, “mild upper lobe predominant emphysema (ULE)”, “airway-predomi...

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Literature Corpus work: 24b3190a-b29a-5f54-8d43-d4ba1986cc28
DOI: 10.1101/2022.01.11.22268818

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