Article
Machine Learning Characterization of COPD Subtypes: Insights From the COPDGene Study.
Chest - 1 May 2020
Castaldi Peter J, Boueiz Adel, Yun Jeong, Estepar Raul San Jose, Ross James C, Washko George, Cho Michael H, Hersh Craig P, Kinney Gregory L, Young Kendra A, Regan Elizabeth A, Lynch David A, Criner Gerald J, Dy Jennifer G, Rennard Stephen I, Casaburi Richard, Make Barry J, Crapo James, Silverman Edwin K, Hokanson John E
Abstract excerpt
COPD is a heterogeneous syndrome. Many COPD subtypes have been proposed, but there is not yet consensus on how many COPD subtypes there are and how they should be defined. The COPD Genetic Epidemiology Study (COPDGene), which has generated 10-year longitudinal chest imaging, spirometry, and molecular data, is a rich resource for relating COPD phenotypes to underlying genetic and molecular mechanisms. In this...
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